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BASEM awards researchers at Congress 2007 | Autumn 2007

DJO/Aircast continued their support for two annual Awards presented at this year’s BASEM Congress (3rd-5th October): the DJO/Aircast Clinical Scientific Researcher Award and the DJO/Aircast Basic Scientific Researcher Award.

Dr Anthony Kehoe won this year’s Aircast Clinical Scientific Researcher Award for his paper which he presented entitled ‘Bradykinin Receptor Gene Variant Predicts Stress Fracture in Young Caucasian Men’ in which he set out to establish if the B2 receptor +9/-9 polymorphism predicts stress fracture during Royal Marines (RM) recruit training. The study is the first to provide data to identify a genetic risk factor for stress fracture. Genotyping offers a potential tool for risk-stratification in susceptible groups and the B2 receptor may become an attractive pharmacological target for the prevention and treatment of stress fracture.

Anthony is a Specialist Registrar in Emergency Medicine at St Barts & The Royal London Hospital, where he works with HEMS (Helicopter Emergency Medical Services). His co-authors are Fotios Drenos, Kawah Li and Hugh Montgomery.

Anthony commented: “The inspiration for my study came from Hugh Montgomery at the Institute of Human Health and Performance, UCL where I was attached as a research fellow. They were involved in ongoing research into the genetics of bone and muscle physiology and kindly agreed to fund the study. The Institute of Naval Medicine is my parent organisation and they contributed to the study design and securing us access to RM recruits.”

The second Award, the DJO/Aircast Basic Scientific Researcher Award was awarded to Mario Ronga, MD, from the Dept. of Orthopaedic & Traumatology and the Dept of Experimental Biomedical & Clinical Science at the University of Insubria, Varese, Italy in collaboration with his colleagues Evgenia Karousou PhD, Davide Vigette PhD, Alberto Passi, MD,PhD, and Nicola Maffulli MD, MS, PhD,FRCS(Orth) from the Dept. of Trauma & Orthopaedic Surgery at Keele University School of Medicine, UK for their paper entitled “Gene expression & protein analysis in ruptured human Achilles tendons” - a comparison between ruptured and healthy area”.

They studied the extracellular matrix of 19 ruptured human Achilles tendons, comparing the tissue composition of specimens harvested from the area close to the rupture with specimens harvested from an apparently healthy area in the same tendon. The hypothesis was that the metabolism of these molecules is altered in patients with Achilles tendon rupture.
 

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